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To slow kidney function decline in adults with primary IgAN at risk of disease worsening, take a different path for your IgAN

To slow kidney function decline in adults with primary IgAN at risk of disease worsening
TAKE A DIFFERENT PATH FOR YOUR IgAN

FABHALTA is the first and only FDA-approved oral IgAN treatment that targets the alternative complement pathway, a part of the immune system

What is IgAN, and how can it affect my kidneys?

IgAN is a chronic disease that may worsen over time and impact kidney function, which is how well the kidneys are working. Signs that IgAN is getting worse include ongoing high levels of protein in urine (proteinuria) and loss of kidney function. In a study of 655 adult patients with primary IgAN, ~1 in 6 lost 50% or more of their kidney function (based on eGFR) within 3 years of diagnosis.

This was from a study that looked back at patient records from a California healthcare system in those diagnosed with IgAN. The purpose of this study was to assess multiple kidney outcomes. At the start of study, patients were on different treatments; 70% were on an ACEi or ARB with limited use of other therapies. At the start of study, the average eGFR was 59.9 mL/min/1.73 m2 and average UPCR 2.5 g/g.

What is FABHALTA?

FABHALTA is a targeted approach that may offer what you are looking for:

  • Oral dosing with or without food. Take one capsule twice a day
  • The only oral IgAN treatment targeting the alternative pathway within the complement system, a part of the immune system that is thought to contribute to IgAN
  • Backed by clinical evidence. Tested in a large clinical study of 477 adults with primary IgAN over 24 months
  • A prescription medicine used to slow kidney function decline in adults with primary IgAN, who are at risk of their disease getting worse

See how FABHALTA helped slow kidney function decline

TK

IgAN, immunoglobulin A nephropathy.